Moderna edges Pfizer in new US analysis

New analysis demonstrates Moderna vaccine’s superiority over the Pfizer vaccine — AFP/File
  • The Moderna vaccine was 93% efficient in opposition to hospitalisation whereas Pfizer was 88% efficient.
  • The examine additionally features a separate evaluation of the degrees of several types of antibodies provoked by the vaccines.
  • The Moderna vaccine elicited larger ranges of antibodies in comparison with Pfizer and J&J for a key a part of the virus’ spike protein.

WASHINGTON: Moderna confers higher long-term safety in opposition to hospitalisation than Pfizer, suggests a latest examine launched by the US Facilities for Illness Management and Prevention (CDC) on Friday.

CDC researchers carried out an evaluation of practically 3,689 adults who had been hospitalised with extreme COVID-19 from March 11 to August 15, 2021 — a interval that precedes and contains the dominance of the Delta variant.

Total, 12.9 % had been absolutely vaccinated with the Moderna vaccine, 20.0 % had been vaccinated with Pfizer-BioNTech, and three.1 % had been vaccinated with Johnson & Johnson.

Over your entire interval, the Moderna vaccine was 93% efficient in opposition to hospitalisation, Pfizer was 88% efficient, and J&J was 68% efficient.

The lack of efficacy in opposition to hospitalisation for Pfizer was notably pronounced: it fell from 91% in 14-120 days after vaccination to 77% greater than 120 days after vaccination.

Against this, Moderna fell from 93% to 92% when evaluating the identical two durations.

The examine additionally included a separate evaluation of the degrees of several types of antibodies provoked by the vaccines, taken from 100 volunteers.

The Moderna vaccine elicited larger ranges of antibodies in comparison with Pfizer and J&J for a key a part of the virus’ spike protein, which it makes use of to invade cells.

There may be accumulating analysis suggesting the Moderna vaccine’s superiority over the Pfizer vaccine, together with earlier CDC research launched final week.

The explanations aren’t absolutely clear, however it might be as a result of the dosage ranges are larger — 100 micrograms in opposition to 30.

It is also tied to the dosing interval, with the Pfizer photographs given three weeks aside versus Moderna, that are given 4 weeks aside.

The Meals and Drug Administration was holding a gathering of main impartial consultants on Friday to weigh the query of giving third doses of Pfizer to the final inhabitants, not simply immune-compromised folks.

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